Use weekly for collagen stimulation and serum absorption. Orbital rim stem cell treatment. Botox alternative. Great add on to facial treatment. Use with Super Sun Removal post-procedure lotionfor faster results and sun spot removal. Use on hands with the serum to smooth and rejuvenate skin. For Dr. Pen Ultima A6 fit. Rezenuration. 50 pieces or 100 pieces Nano pro pack. Fits A6 models.